Book Holiday Homes in De Soto

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Featured Holiday Homes in De Soto

Charming 1-bedroom house in nice Imperial with AC.  Attn! Traveling Contractors

Charming 1-bedroom house in nice Imperial with AC. Attn! Traveling Contractors

Imperial
Stay at this vacation home in Imperial. Enjoy air conditioning. Popular attractions Mastodon State Historic Site and Kimmswick Historical Society Museum are ...
Charming 1-bedroom house in nice Imperial with AC. Attn! Traveling Contractors
Clifford's Country Cottage

Clifford's Country Cottage

2.5 out of 5
Bonne Terre
The price is NZ$258 per night from 12 Aug to 13 Aug
NZ$258
12 Aug - 13 Aug
includes taxes & fees
Stay at this vacation home in Bonne Terre. Enjoy laundry facilities, cable/satellite TV service, and an in-room coffeemaker. Popular attractions Bonne Terre ...
Clifford's Country Cottage
Your home away from home in downtown, historic Farmington!

Your home away from home in downtown, historic Farmington!

Farmington
The price is NZ$342 per night from 17 Aug to 18 Aug
NZ$342
17 Aug - 18 Aug
includes taxes & fees
Book a stay at this family-friendly vacation home in Farmington. Enjoy free WiFi, a water park, and a garden. Popular attractions Wilson Rozier Park and Bicentennial ...
Your home away from home in downtown, historic Farmington!
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Cozy Three bedroom home in Central Farmington

Cozy Three bedroom home in Central Farmington

Farmington
The price is NZ$412 per night from 17 Aug to 18 Aug
NZ$412
17 Aug - 18 Aug
includes taxes & fees
Stay at this vacation home in Farmington. Enjoy free WiFi, laundry facilities, and an in-room coffeemaker. Popular attractions Trimfoot Park and Harlan Park ...
Cozy Three bedroom home in Central Farmington
Charming 3-bedroom house with WiFi, and fenced-in backyard in serene Byrnes Mill

Charming 3-bedroom house with WiFi, and fenced-in backyard in serene Byrnes Mill

2 out of 5
Byrnes Mill
Stay at this vacation home in House Springs. Enjoy a fitness center, a garden, and laundry facilities. Popular attractions Brynes Mill Park and Rockford Beach ...
Charming 3-bedroom house with WiFi, and fenced-in backyard in serene Byrnes Mill
Charming 1-bd house in Downtown Farmington, 1block from Police & Fire stations

Charming 1-bd house in Downtown Farmington, 1block from Police & Fire stations

Farmington
Stay at this vacation home in Farmington. Enjoy free WiFi, laundry facilities, and an in-room coffeemaker. Popular attractions Farmington Skate Park and Long ...
Charming 1-bd house in Downtown Farmington, 1block from Police & Fire stations
Bluebird Meadows with In-ground Pool and Hot Tub! 125 ACRES TO EXPLORE

Bluebird Meadows with In-ground Pool and Hot Tub! 125 ACRES TO EXPLORE

Park Hills
Book a stay at this family-friendly vacation home in Park Hills. Enjoy free WiFi, private pools, and a water park. Popular attractions St. Joe State Park and ...
Bluebird Meadows with In-ground Pool and Hot Tub! 125 ACRES TO EXPLORE
Peter Ray House

Peter Ray House

Maeystown
The price is NZ$378 per night from 10 Aug to 11 Aug
NZ$378
10 Aug - 11 Aug
includes taxes & fees
Stay at this vacation home in Maeystown. Enjoy free WiFi, a garden, and laundry facilities. Popular attraction Illinois Caverns State Natural Area is located ...
Peter Ray House
The Shack- 3 bedroom finished house

The Shack- 3 bedroom finished house

Leadwood
Stay at this vacation home in Park Hills. Enjoy laundry facilities, an in-room coffeemaker, and air conditioning. Popular attractions Missouri Mines State Historic ...
The Shack- 3 bedroom finished house
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

De Soto Holiday Houses

Do you love last minute road trips and late-night food runs and sunrises on the beach? Do words like “schedule” and “calendar” make you shout, “Don’t box me in!”? You might be a little bit of a rebel. But you’re a rebel with a cause: having a smashing holiday. Itinerary? What’s that? Our De Soto vacation homes are the perfect way for you to wing it.

Holiday houses in De Soto let you live life on your own terms. You’ll have so much space, you’ll wish you had more friends and family—but you can always invite over the neighbours. You can often have luxury amenities, but with all the attractions of De Soto in your backyard, budget holiday homes will do just fine, too. That will just leave you more dough to spend on the important things: cocktails, brunch, and local De Soto adventures, obvs.

If your adventure buddy happens to have fur and four legs, you just might find a pet-friendly holiday house in De Soto with your name on it.

No need to spend big bickies for a holiday beach house the size of Buckingham Palace—unless you’re really in trouble with bae. We’ve got a great selection of De Soto vacation homes with everything you need for a seriously amazing getaway. Throw out that daily planner and hit “reject” on all those meeting invites. You’re off to a place where there are no rules.

De Soto Holiday Homes essential information

Accommodation
63 Holiday Homes
Lowest Price
NZ$258
Highest Price
NZ$435
Popular accommodation
Charming 1-bedroom house in nice Imperial with AC. Attn! Traveling Contractors, Clifford's Country Cottage, Your home away from home in downtown, historic Farmington!, Cozy Three bedroom home in Central Farmington, Charming 3-bedroom house with WiFi, and fenced-in backyard in serene Byrnes Mill, Charming 1-bd house in Downtown Farmington, 1block from Police & Fire stations, Bluebird Meadows with In-ground Pool and Hot Tub! 125 ACRES TO EXPLORE, Peter Ray House, The Shack- 3 bedroom finished house

Top trending hotels in De Soto

Holiday Inn Club Vacations Timber Creek Resort at De Soto by IHG

Holiday Inn Club Vacations Timber Creek Resort at De Soto by IHG

3.5 out of 5
4800 U.S. Highway 67, De Soto, MO
Fully refundable
The price is NZ$291 per night from 11 Aug to 12 Aug
NZ$291
11 Aug - 12 Aug
includes taxes & fees
Stay at this 3.5-star family-friendly aparthotel in De Soto. Enjoy free parking, an outdoor pool, and a fitness center. Our guests praise the property condition ...
Holiday Inn Club Vacations Timber Creek Resort at De Soto by IHG
Pool, Lake & Patio: Sweeping De Soto Estate

Pool, Lake & Patio: Sweeping De Soto Estate

De Soto
Book a stay at this family-friendly property in De Soto. Enjoy private pools, a garden, and laundry facilities. Popular attractions Valle Lake Beach and Clear ...
Pool, Lake & Patio: Sweeping De Soto Estate
82 Acre Hobby Farm with Lincoln Log Cabin

82 Acre Hobby Farm with Lincoln Log Cabin

De Soto
The price is NZ$435 per night from 16 Aug to 17 Aug
NZ$435
16 Aug - 17 Aug
includes taxes & fees
Stay at this cabin in De Soto. Enjoy a garden, laundry facilities, and patios. Popular attractions Eastside Community Park and Ritcher Park are located ...
82 Acre Hobby Farm with Lincoln Log Cabin
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Lakeside Private Villa | 5-Hole Golf On-Site

Lakeside Private Villa | 5-Hole Golf On-Site

4800 US Highway 67, Desoto, MO
Fully refundable
The price is NZ$310 per night from 17 Aug to 18 Aug
NZ$310
17 Aug - 18 Aug
includes taxes & fees
Stay at this villa in De Soto. Enjoy free WiFi, a sauna, and cable/satellite TV service. Popular attractions Valle Lake Beach and Clear Lake are located ...
Lakeside Private Villa | 5-Hole Golf On-Site
Don't see what you're looking for?
See all available properties in De Soto
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

**Terms and Conditions apply.
^Subject to availability and chosen travel dates.