Book Holiday Homes in Santa Isabel

Start date: Check-in selected.
End date: Check-out

More Flash, Less Cash - Take advantage of our Price Pledge** (even on luxey stays)

We keep it easy with the option to pay now or later on select accommodation

Book up 'til the last second - millions of rooms to crash tonight^

Featured Holiday Homes in Santa Isabel

3-bedroom house in Coamo with AC on bedroom 1

3-bedroom house in Coamo with AC on bedroom 1

Coamo, Pr
Enjoy free WiFi, a garden, and laundry facilities. Popular attractions Coamo Historical Museum and Coamo Springs are located nearby.
Opens in a new window3-bedroom house in Coamo with AC on bedroom 1
Ponce holiday apartment

Ponce holiday apartment

Ponce
Stay at this vacation home in Ponce. Enjoy free WiFi, a garden, and laundry facilities. Popular attractions Carribbean Cinemas Ponce Towne and Playa Hilton Ponce ...
Opens in a new windowPonce holiday apartment
Oasis Salinas

Oasis Salinas

Salinas
The price is NZ$230 per night from 18 Sept to 19 Sept
NZ$230
18 Sept - 19 Sept
includes taxes & fees
Stay at this vacation home in Salinas. Enjoy laundry facilities, air conditioning, and a hot tub. Popular attractions Marina de Salinas and Playa La Ochenta ...
Opens in a new windowOasis Salinas
Save an average of 15% on thousands of hotels when you're signed in
Beautiful & Relaxing Cottage House-2br/1.5 bath- with great mountain views.

Beautiful & Relaxing Cottage House-2br/1.5 bath- with great mountain views.

Barranquitas
Stay at this vacation home in Barranquitas. Enjoy free WiFi, a fitness center, and a garden. Popular attraction Finca Don Felix para la Naturaleza is located ...
Opens in a new windowBeautiful & Relaxing Cottage House-2br/1.5 bath- with great mountain views.
Tropical Ponce Home: Private Pool & Outdoor Oasis!

Tropical Ponce Home: Private Pool & Outdoor Oasis!

Ponce
Stay at this vacation home in Ponce. Enjoy private pools, a garden, and laundry facilities. Popular attractions El Museo Castillo Serralles and El Vigia Observation ...
Opens in a new windowTropical Ponce Home: Private Pool & Outdoor Oasis!
Oceanfront Escape, Hammocks, Walk to Boardwalk Solar Backup

Oceanfront Escape, Hammocks, Walk to Boardwalk Solar Backup

Arroyo
Book a stay at this beach vacation home in Arroyo. Enjoy free WiFi, a beach locale, and a water park. Popular attractions Balneario Punta Guilarte and Playa ...
Opens in a new windowOceanfront Escape, Hammocks, Walk to Boardwalk Solar Backup
Casita La Ley en Cayey with 2-bedroom AC & WiFi.

Casita La Ley en Cayey with 2-bedroom AC & WiFi.

Cayey
Stay at this vacation home in Cayey. Enjoy laundry facilities and air conditioning. Popular attractions Carribbean Cinemas Cayey and Carite State Forest are ...
Opens in a new windowCasita La Ley en Cayey with 2-bedroom AC & WiFi.
Grandpa's lake house lake private access mountain view museum 1950's experience

Grandpa's lake house lake private access mountain view museum 1950's experience

Cidra
The price is NZ$185 per night from 18 Sept to 19 Sept
NZ$185
18 Sept - 19 Sept
includes taxes & fees
Stay at this vacation home in Cidra. Enjoy a garden, laundry facilities, and housekeeping. Popular attractions Carribbean Cinemas Cayey and Jardin Botanico y ...
Opens in a new windowGrandpa's lake house lake private access mountain view museum 1950's experience
CARIBBEAN 181 - Modern Beachfront House

CARIBBEAN 181 - Modern Beachfront House

Guayama
Stay at this vacation home in Guayama. Enjoy free WiFi, private pools, and cable/satellite TV service. Popular attractions Playa Pozuelo and Reserva Nacional ...
Opens in a new windowCARIBBEAN 181 - Modern Beachfront House
Don't see what you're looking for?
See all available properties in Santa Isabel
View all properties
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Santa Isabel Holiday Houses

Do you love last minute road trips and late-night food runs and sunrises on the beach? Do words like “schedule” and “calendar” make you shout, “Don’t box me in!”? You might be a little bit of a rebel. But you’re a rebel with a cause: having a smashing holiday. Itinerary? What’s that? Our Santa Isabel vacation homes are the perfect way for you to wing it.

Holiday houses in Santa Isabel let you live life on your own terms. You’ll have so much space, you’ll wish you had more friends and family—but you can always invite over the neighbours. You can often have luxury amenities, but with all the attractions of Santa Isabel in your backyard, budget holiday homes will do just fine, too. That will just leave you more dough to spend on the important things: cocktails, brunch, and local Santa Isabel adventures, obvs.

If your adventure buddy happens to have fur and four legs, you just might find a pet-friendly holiday house in Santa Isabel with your name on it.

No need to spend big bickies for a holiday beach house the size of Buckingham Palace—unless you’re really in trouble with bae. We’ve got a great selection of Santa Isabel vacation homes with everything you need for a seriously amazing getaway. Throw out that daily planner and hit “reject” on all those meeting invites. You’re off to a place where there are no rules.

Santa Isabel Holiday Homes essential information

Accommodation
101 Holiday Homes
Lowest Price
NZ$185
Highest Price
NZ$861
Popular accommodation
3-bedroom house in Coamo with AC on bedroom 1, Ponce holiday apartment, Oasis Salinas , Beautiful & Relaxing Cottage House-2br/1.5 bath- with great mountain views., Tropical Ponce Home: Private Pool & Outdoor Oasis!, Oceanfront Escape, Hammocks, Walk to Boardwalk Solar Backup, Casita La Ley en Cayey with 2-bedroom AC & WiFi., Grandpa's lake house lake private access mountain view museum 1950's experience, CARIBBEAN 181 - Modern Beachfront House

Top trending hotels in Santa Isabel

Hotel Las Vegas

Hotel Las Vegas

3 out of 5
PR 153, Km 2.9, Santa Isabel
Stay at this 3-star motel in Santa Isabel. Enjoy 24-hour room service, a 24-hour front desk, and daily housekeeping. Our guests praise the helpful staff and ...
Opens in a new windowHotel Las Vegas
Hacienda del Sur

Hacienda del Sur

2 out of 5
Carr 545 KM 1.5, Sector Gabia, Santa Isabel
The price is NZ$279 per night from 25 Sept to 26 Sept
NZ$279
25 Sept - 26 Sept
includes taxes & fees
Stay at this hotel in Santa Isabel. Enjoy free WiFi, free parking, and cable TV channels. Popular attractions Carribbean Cinemas Santa Isabel and Coamo Springs ...
Opens in a new windowHacienda del Sur
Cultural Oasis: Beachfront Gem, Puerto Rican Heritage at Your Doorstep

Cultural Oasis: Beachfront Gem, Puerto Rican Heritage at Your Doorstep

Santa Isabel
The price is NZ$608 per night from 18 Sept to 19 Sept
NZ$608
18 Sept - 19 Sept
includes taxes & fees
Book a stay at this beach vacation home in Santa Isabel. Enjoy free WiFi, a beach locale, and laundry facilities. Popular attractions Playa La Ochenta and Carribbean ...
Opens in a new windowCultural Oasis: Beachfront Gem, Puerto Rican Heritage at Your Doorstep
Save an average of 15% on thousands of hotels when you're signed in
Home in Santa Isabel, Puerto Rico. 4BR 2BA home with WiFi, AC & UNDERGROUND POOL

Home in Santa Isabel, Puerto Rico. 4BR 2BA home with WiFi, AC & UNDERGROUND POOL

Santa Isabel
The price is NZ$861 per night from 18 Sept to 19 Sept
NZ$861
18 Sept - 19 Sept
includes taxes & fees
Book a stay at this family-friendly vacation home in Santa Isabel. Enjoy free WiFi, laundry facilities, and balconies. Popular attractions Carribbean Cinemas ...
Opens in a new windowHome in Santa Isabel, Puerto Rico. 4BR 2BA home with WiFi, AC & UNDERGROUND POOL
Don't see what you're looking for?
See all available properties in Santa Isabel
View all properties
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

**Terms and Conditions apply.
^Subject to availability and chosen travel dates.