Book Holiday Homes in Panama City

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Featured Holiday Homes in Panama City

Two Floors Duplex in the middle of Panama City.

Two Floors Duplex in the middle of Panama City.

Panamá Panamá
Stay at this holiday home in Panama City. Enjoy private pools, laundry facilities and patios. Popular attractions Via Espana and Multiplaza Pacific Mall are ...
Opens in a new windowTwo Floors Duplex in the middle of Panama City.
Oasis with pool near panama canal

Oasis with pool near panama canal

Panamá Provincia de Panamá
Stay at this holiday home in Panama City. Enjoy free Wi-Fi, private pools and a garden. Popular attractions Miraflores Locks and Albrook Shopping Mall are located ...
Opens in a new windowOasis with pool near panama canal
Panama View House – A Hilltop Retreat with Stunning Canal Views

Panama View House – A Hilltop Retreat with Stunning Canal Views

Panama City Panamá Province
Stay at this holiday home in Panama City. Enjoy laundry facilities and air conditioning. Popular attractions Amador Causeway and Albrook Shopping Mall are located ...
Opens in a new windowPanama View House – A Hilltop Retreat with Stunning Canal Views
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Tropical House with Historic Charm, WiFi, Private Bathrooms and Workspaces

Tropical House with Historic Charm, WiFi, Private Bathrooms and Workspaces

Panamá Provincia de Panamá
Stay at this holiday home in Panama City. Enjoy laundry facilities, patios and air conditioning. Popular attractions Albrook Shopping Mall and Cinta Costera ...
Opens in a new windowTropical House with Historic Charm, WiFi, Private Bathrooms and Workspaces
Studio Coliving Junior Suite

Studio Coliving Junior Suite

Panama Panama
Stay at this holiday home in Panama City. Enjoy cable/satellite TV service, air conditioning and an outdoor pool. Popular attractions Albrook Shopping Mall and ...
Opens in a new windowStudio Coliving Junior Suite
Downtown Villa with Private Pool & Bar

Downtown Villa with Private Pool & Bar

Panamá Provincia de Panamá
Stay at this business-friendly holiday home in Panama City. Enjoy private pools, breakfast (surcharge) and a garden. Popular attractions Multiplaza Pacific Mall ...
Opens in a new windowDowntown Villa with Private Pool & Bar
Panama View House

Panama View House

Panamá Provincia de Panamá
Stay at this holiday home in Panama City. Enjoy laundry facilities and air conditioning. Popular attractions Amador Causeway and Albrook Shopping Mall are located ...
Opens in a new windowPanama View House
Apartamento a 10 minutos del aeropuerto

Apartamento a 10 minutos del aeropuerto

Panamá Panama
Stay at this holiday home in Las Mañanitas. Enjoy free Wi-Fi, a garden and laundry facilities. Popular attractions Metromall Panama and Los Pueblos Commercial ...
Opens in a new windowApartamento a 10 minutos del aeropuerto
Breathtaking Views Mansion w/King Beds

Breathtaking Views Mansion w/King Beds

Panamá Provincia de Panamá
Stay at this holiday home in Panama City. Enjoy a garden, laundry facilities and a pool table. Popular attractions Via Espana and Multiplaza Pacific Mall are ...
Opens in a new windowBreathtaking Views Mansion w/King Beds
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Panama City Holiday Houses

Do you love last minute road trips and late-night food runs and sunrises on the beach? Do words like “schedule” and “calendar” make you shout, “Don’t box me in!”? You might be a little bit of a rebel. But you’re a rebel with a cause: having a smashing holiday. Itinerary? What’s that? Our Panama City vacation homes are the perfect way for you to wing it.

Holiday houses in Panama City let you live life on your own terms. You’ll have so much space, you’ll wish you had more friends and family—but you can always invite over the neighbours. You can often have luxury amenities, but with all the attractions of Panama City in your backyard, budget holiday homes will do just fine, too. That will just leave you more dough to spend on the important things: cocktails, brunch, and local Panama City adventures, obvs.

If your adventure buddy happens to have fur and four legs, you just might find a pet-friendly holiday house in Panama City with your name on it.

No need to spend big bickies for a holiday beach house the size of Buckingham Palace—unless you’re really in trouble with bae. We’ve got a great selection of Panama City vacation homes with everything you need for a seriously amazing getaway. Throw out that daily planner and hit “reject” on all those meeting invites. You’re off to a place where there are no rules.

Panama City Holiday Homes essential information

Accommodation
73 Holiday Homes
Lowest Price
NZ$206
Highest Price
NZ$380
Popular accommodation
Two Floors Duplex in the middle of Panama City., Oasis with pool near panama canal, Panama View House – A Hilltop Retreat with Stunning Canal Views, Tropical House with Historic Charm, WiFi, Private Bathrooms and Workspaces, Studio Coliving Junior Suite, Downtown Villa with Private Pool & Bar, Panama View House, Apartamento a 10 minutos del aeropuerto, Breathtaking Views Mansion w/King Beds

Top trending hotels in Panama City

Hotel Riu Plaza Panama

Hotel Riu Plaza Panama

5 out of 5
Calle 50, Urb. Marbella Panama City Panama
Fully refundableReserve now, pay when you stay
The price is NZ$294 per night from 30 Mar to 31 Mar
NZ$294
30 Mar - 31 Mar
includes taxes & fees
Stay at this luxury hotel in Panama City. Enjoy free breakfast, free Wi-Fi and 3 restaurants. Our guests praise the breakfast and the pool in their reviews. ...
Opens in a new windowHotel Riu Plaza Panama
Sheraton Grand Panama

Sheraton Grand Panama

4 out of 5
Via Israel And 77th Street Panama City Panama
Fully refundableReserve now, pay when you stay
The price is NZ$252 per night from 3 Apr to 4 Apr
NZ$252
3 Apr - 4 Apr
includes taxes & fees
Stay at this spa resort in Panama City. Enjoy free Wi-Fi, free parking and a full-service spa. Our guests praise the helpful staff and the property condition ...
Opens in a new windowSheraton Grand Panama
Hotel El Panama by Faranda Grand, a member of Radisson Individuals

Hotel El Panama by Faranda Grand, a member of Radisson Individuals

4 out of 5
Via Espana 111 Panama City Panama
Fully refundableReserve now, pay when you stay
The price is NZ$206 per night from 23 Mar to 24 Mar
NZ$206
23 Mar - 24 Mar
includes taxes & fees
Stay at this spa hotel in Panama City. Enjoy free breakfast, free parking and a full-service spa. Our guests praise the helpful staff in their reviews. Popular ...
Opens in a new windowHotel El Panama by Faranda Grand, a member of Radisson Individuals
Save an average of 15% on thousands of hotels when you're signed in
W Panama

W Panama

5 out of 5
Calle Aquilino de la Guardia & Calle 50 Panama City
Fully refundableReserve now, pay when you stay
The price is NZ$380 per night from 31 Mar to 1 Apr
NZ$380
31 Mar - 1 Apr
includes taxes & fees
Stay at this luxury hotel in Panama City. Enjoy 2 restaurants, 3 hot tubs and 2 bars/lounges. Our guests praise the helpful staff in their reviews. Popular attractions ...
Opens in a new windowW Panama
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

**Terms and Conditions apply.
^Subject to availability and chosen travel dates.