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Featured Southeast Missouri Luxury Hotels

Super 8 by Wyndham Pevely

Motel 6 Poplar Bluff, MO

Days Inn and Suites by Wyndham Sikeston

Historical 'Kage House' Short Term Rental located in "Old Town Cape"

Pear Tree Inn Cape Girardeau Near the Medical Center

Comfort Inn Festus - St Louis South

Super 8 by Wyndham Poplar Bluff Missouri

Quality Inn Festus

Quality Inn
Luxury Hotels & Resorts in Southeast Missouri
What’s a holiday without a few upgrades here and there? Your busy life calls for an especially luxurious escape—even if you did just start thinking about it, and your annual leave starts tomorrow. But you don’t have to sacrifice A-list amenities and top-shelf touches just because you need to make a break for it; find luxury hotels in Southeast Missouri on lastminute.co.nz that’ll have you sinking into soft down pillows before Janice in accounting can catch up with you.
You may not be a celebrity, but there’s no reason you can’t be treated like one. Whether you require 2,000-thread-count sheets, perfectly veined Italian marble or down pillows made from the golden goose itself, luxury hotels near Southeast Missouri can deliver all that and more. Many of your accommodation options will offer oenophiles the chance to sip (or swill) prime wines, while fromage fanatics can chow down on fancy brie and camembert to their heart’s content. Need some sustenance to really soak up that wine? Now’s your chance to splurge on room service—it’s almost like having your own personal butler…almost.
Treat yo’self. Finding and booking our Southeast Missouri luxury hotels is a piece of cake. And speaking of cake—it should be delicious at your lavish lodging. So listen to your inner Paris Hilton and indulge yourself with the best of the best dining, service and comfort. With our discounts, you don’t have to be a regular at Tiffany & Co. to book the getaway of your dreams.
Southeast Missouri hotels essential information
Accommodation | 577 hotels |
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Lowest Price | |
Highest Price | |
Popular hotels | Super 8 by Wyndham Pevely, Motel 6 Poplar Bluff, MO, Days Inn and Suites by Wyndham Sikeston, Historical 'Kage House' Short Term Rental located in "Old Town Cape" , Pear Tree Inn Cape Girardeau Near the Medical Center, Comfort Inn Festus - St Louis South, Super 8 by Wyndham Poplar Bluff Missouri, Quality Inn Festus, Quality Inn |
Most recent Southeast Missouri hotel reviews

More Luxury Hotels
Other cities near Southeast Missouri
- Chesterfield Hotels
- Cape Girardeau Hotels
- Carbondale Hotels
- Fenton Hotels
- Eminence Hotels
- Sikeston Hotels
- Eureka Hotels
- Ozarks Hotels
- Poplar Bluff Hotels
- Farmington Hotels
- Cuba Hotels
- East St. Louis Hotels
- Richmond Heights Hotels
- Van Buren Hotels
- Kirkwood Hotels
- Arnold Hotels
- Hardy Hotels
- Brentwood Hotels
- West Plains Hotels
- Southern Illinois Hotels
Other top Southeast Missouri hotels
- Baymont Inn and Suites by Wyndham Farmington, MO
- Drury Plaza Hotel Cape Girardeau Conference Center
- La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau
- Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG
- Motel 6 Poplar Bluff, MO
- Fairfield Inn & Suites by Marriott Poplar Bluff
- Candlewood Suites Cape Girardeau by IHG
- Pear Tree Inn Cape Girardeau West
- Best Western Plus Sikeston
- Drury Inn & Suites Sikeston, MO
- Pear Tree Inn Cape Girardeau Near the Medical Center
- Days Inn and Suites by Wyndham Sikeston
- Courtyard by Marriott Cape Girardeau Downtown
- Holiday Inn Express & Suites Perryville by IHG
- Comfort Inn Festus - St Louis South
- Drury Inn & Suites Hayti Caruthersville
- Drury Inn & Suites Jackson MO
- Quality Inn