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Holiday Inn Express & Suites St. Louis South - I-55 by IHG

2.5 star property

Photo gallery for Holiday Inn Express & Suites St. Louis South - I-55 by IHG

Property amenity
Free daily buffet breakfast
Exterior
Property amenity
Fitness facility

Reviews

9.6 out of 10
Exceptional

Popular amenities

  • Free Wi-Fi
  • Air-conditioning

Explore the area

View map
4250 Midamerica Lane, St. Louis, MO, 63129
  • Place, Barnes Jewish South Campus
    ‪5 min walk‬
  • Place, Busch Stadium
    ‪16 min drive‬
  • Place, St. Louis Union Station
    ‪18 min drive‬
  • Airport, St. Louis, MO (STL-Lambert-St. Louis Intl.)
    ‪30 min drive‬

Room options

View all photos for Standard Room, 2 Queen Beds, Accessible (Comm, Bath Shwr Combo)

Room amenity

Standard Room, 2 Queen Beds, Accessible (Comm, Bath Shwr Combo)

9.4 out of 10
Exceptional
(13 reviews)
  • 28 sq m
  • 1 bedroom
  • Sleeps 4
  • 2 Queen Beds

View all photos for Standard Room, 2 Queen Beds, Accessible (Mobil Tub)

Standard Room, 2 Queen Beds, Accessible (Mobil Tub)

Standard Room, 2 Queen Beds, Accessible (Mobil Tub)

9.6 out of 10
Exceptional
(4 reviews)
  • 28 sq m
  • 1 bedroom
  • Sleeps 4
  • 2 Queen Beds

View all photos for Suite, 1 Bedroom (2 Queen, Extra Living Area)

Room amenity

Suite, 1 Bedroom (2 Queen, Extra Living Area)

9.4 out of 10
Exceptional
(29 reviews)
  • 28 sq m
  • 1 bedroom
  • Sleeps 6
  • 2 Queen Beds

View all photos for Standard Room, 1 King Bed, Accessible (Comm, Bath Shower Combo)

Room amenity

Standard Room, 1 King Bed, Accessible (Comm, Bath Shower Combo)

9.0 out of 10
Wonderful
(7 reviews)
  • 28 sq m
  • 1 bedroom
  • Sleeps 4
  • 1 King Bed

View all photos for Standard Room, 1 King Bed, Accessible (Mobil Roll In Shwr)

Free toiletries, hair dryer, towels, soap

Standard Room, 1 King Bed, Accessible (Mobil Roll In Shwr)

10.0 out of 10
Exceptional
(2 reviews)
  • 28 sq m
  • 1 bedroom
  • Sleeps 2
  • 1 King Bed

View all photos for Suite, 1 King Bed (Extra Living, Walk in Shwr)

Suite, 1 King Bed (Extra Living, Walk in Shwr)

Suite, 1 King Bed (Extra Living, Walk in Shwr)

9.0 out of 10
Wonderful
(4 reviews)
  • 28 sq m
  • 1 bedroom
  • Sleeps 4
  • 1 King Bed

View all photos for Standard Room, 1 King Bed (Bath Shwr Combo)

Room amenity

Standard Room, 1 King Bed (Bath Shwr Combo)

9.6 out of 10
Exceptional
(17 reviews)
  • 28 sq m
  • 1 bedroom
  • Sleeps 4
  • 1 King Bed

View all photos for Standard Room

Standard Room

Standard Room

  • 28 sq m
  • 1 bedroom
  • Sleeps 2
  • 1 Single Bed

View all photos for Suite, 1 King Bed, Accessible (Mobil Tub, Extra Living)

Suite, 1 King Bed, Accessible (Mobil Tub, Extra Living)

Suite, 1 King Bed, Accessible (Mobil Tub, Extra Living)

  • 28 sq m
  • 1 bedroom
  • Sleeps 4
  • 1 King Bed

View all photos for Standard Room, 2 Queen Beds

Room amenity

Standard Room, 2 Queen Beds

9.4 out of 10
Exceptional
(74 reviews)
  • 28 sq m
  • 1 bedroom
  • Sleeps 4
  • 2 Queen Beds

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About the area

St. Louis

Located in St. Louis, Holiday Inn Express & Suites St. Louis South - I-55 by IHG is in the business district, within a 5-minute drive of Barnes Jewish South Campus and BounceU of St. Louis. .This hotel is 12.4 mi (20 km) from Forest Park and 13.4 mi (21.5 km) from St. Louis Zoo.

What's nearby

  • Barnes Jewish South Campus - 5 min walk - 0.4 km
  • Busch Stadium - 16 min drive - 27.2 km
  • Enterprise Center - 17 min drive - 26.8 km
  • St. Louis Union Station - 18 min drive - 27.2 km
  • St. Louis Zoo - 21 min drive - 26.3 km

Getting around

  • Kirkwood Station - 17 min drive
  • St. Louis Lambert Intl. Airport (STL) - 32 min drive

Restaurants

  • ‪Burger King - ‬10 min walk
  • ‪McDonald's - ‬5 min drive
  • ‪Popeyes Louisiana Kitchen - ‬4 min walk
  • ‪Hardee's / Red Burrito - ‬11 min walk
  • ‪Rich & Charlie's Italian Restaurant - ‬3 min drive

About this property

Holiday Inn Express & Suites St. Louis South - I-55 by IHG

Holiday Inn Express & Suites St. Louis South - I-55 by IHG offers 99 accommodations with safes and coffee/tea makers. 49-inch flat-screen televisions come with cable channels. Guests can make use of the in-room refrigerators and microwaves. Bathrooms include complimentary toiletries and hair dryers.

Guests can surf the web using the complimentary wired and wireless Internet access. Business-friendly amenities include desks and phones; free local calls are provided (restrictions may apply). Additionally, rooms include irons/ironing boards and blackout drapes/curtains. Change of towels and change of bedsheets can be requested. Housekeeping is provided daily.

Recreational amenities at the hotel include an indoor pool and a 24-hour fitness center.
Make yourself at home in one of the 99 guestrooms featuring refrigerators and flat-screen televisions. Complimentary wired and wireless internet access keeps you connected, and cable programming provides entertainment. Private bathrooms have complimentary toiletries and hair dryers. Conveniences include safes and desks, as well as phones with free local calls.
Be sure to enjoy recreational amenities including an indoor pool and a 24-hour fitness center. Additional features at this hotel include complimentary wireless internet access, a banquet hall, and a vending machine.
A complimentary buffet breakfast is served daily from 6:00 AM to 9:30 AM.
Featured amenities include a business center, a 24-hour front desk, and a safe deposit box at the front desk. Free self parking is available onsite.
A complimentary buffet breakfast is served each morning between 6:00 AM and 9:30 AM.

Property amenities

Internet

  • Available in all rooms: Free WiFi and wired internet
  • Available in some public areas: Free WiFi

Parking and transport

  • Free self parking on site
  • Limited on-site self parking
  • Wheelchair-accessible parking and van parking available

Food and drink

  • Free buffet breakfast available daily 6:00 AM to 9:30 AM

Things to do

  • 24-hour gym
  • Indoor pool

Family friendly

  • In-room cot
  • In-room microwave
  • In-room refrigerator
  • Indoor pool

Conveniences

  • 24-hour front desk
  • Safe at front desk
  • Vending machine

Guest services

  • Change of bedsheets (on request)
  • Change of towels on request
  • Housekeeping (daily)

Business services

  • Business centre
  • Meeting rooms

Outdoors

  • Pool loungers

Accessibility

  • If you have requests for specific accessibility needs, please contact the property using the information on the reservation confirmation received after booking.
  • Lift
  • Stair-free path to entrance
  • Visual alarms in hallways
  • Well-lit path to entrance
  • Wheelchair accessible (may have limitations)
  • Wheelchair-accessible concierge desk
  • Wheelchair-accessible gym
  • Wheelchair-accessible lounge
  • Wheelchair-accessible parking
  • Wheelchair-accessible path of travel
  • Wheelchair-accessible path to lift
  • Wheelchair-accessible pool
  • Wheelchair-accessible public bathroom
  • Wheelchair-accessible van parking

More

  • 4 floors
  • At least 10% of profits reinvested in community and sustainability
  • Banquet hall
  • No plastic drinking straws
  • Smoke-free property

Room amenities

Bedroom

  • Bedsheets provided
  • Blackout drapes
  • Free cot

Bathroom

  • Free toiletries
  • Hair dryer
  • Private bathroom
  • Shampoo
  • Soap
  • Toilet paper
  • Toothbrush and toothpaste (on request)
  • Towels provided

Entertainment

  • 49-inch flat-screen TV with cable channels

Food and drink

  • Coffee/tea maker
  • Microwave
  • Refrigerator

More

  • Air conditioning (climate-controlled)
  • Connecting rooms available
  • Desk
  • Free local calls
  • Heating
  • Iron/ironing board
  • Laptop workspace
  • Phone
  • Safe

Policies

Check-in

Check-in start time: 3:00 PM; Check-in end time: 2:30 AM
Minimum check-in age: 21

Check-out

Check-out before 11 AM
Contactless check-out available

Special check-in instructions

Front desk staff will greet guests on arrival at the property
Information provided by the property may be translated using automated translation tools

Access methods

Staffed front desk

Pets

Pets not allowed (service animals are welcome, and are exempt from fees)

Children and extra beds

Children are welcome
Free cribs are available on request at the property

Payment types

Important information

You need to know

Extra-person charges may apply and vary depending on property policy
Government-issued photo identification and a credit card, debit card, or cash deposit may be required at check-in for incidental charges
Special requests are subject to availability upon check-in and may incur additional charges; special requests cannot be guaranteed
This property accepts credit cards; cash is not accepted
Safety features at this property include a fire extinguisher
This property affirms that it follows the cleaning and disinfection practices of Clean Promise (IHG)

We should mention

Pool access available from 8 AM to 10 PM
The property has connecting/adjoining rooms, which are subject to availability and can be requested by contacting the property using the number on the booking confirmation
This property welcomes guests of all sexual orientations and gender identities (LGBTQ+ friendly)

Property is also known as

Holiday Inn Express St. Louis South I-55 Hotel
Holiday Inn Express St. Louis South I-55
Inn Express St Louis I55
Holiday Inn Express Suites St. Louis South I 55
Holiday Inn Express Suites St. Louis South I 55 by IHG
Holiday Inn Express Suites St. Louis South I 55 an IHG Hotel
Holiday Inn Express & Suites St. Louis South - I-55 by IHG Hotel

Holiday Inn Express & Suites St. Louis South - I-55 by IHG Reviews

Reviews

9.6

Exceptional

Rating 10 - Excellent. 800 out of 1002 reviews
Rating 8 - Good. 145 out of 1002 reviews
Rating 6 - Okay. 35 out of 1002 reviews
Rating 4 - Poor. 15 out of 1002 reviews
Rating 2 - Terrible. 7 out of 1002 reviews

9.6/10

Cleanliness

9.6/10

Staff & service

9.6/10

Amenities

9.6/10

Property conditions & facilities

Reviews

10/10 Excellent

Rock

Stayed 2 nights in Nov 2025

10/10 Excellent

Samantha

Stayed 1 night in Dec 2025

8/10 Good

Jeffrey

Business traveller
Liked: Cleanliness, staff & service, property conditions & facilities, room comfort
Stayed 4 nights in Dec 2025

4/10 Poor

Dallas

Stayed 1 night in Dec 2025

10/10 Excellent

tiffany

Liked: Cleanliness, amenities, property conditions & facilities
Room was very clean! enjoyed the amenities!
Stayed 1 night in Dec 2025

10/10 Excellent

Melissa

Liked: Cleanliness
Staff was welcoming and helpful at check in. Offered cookies and milk. The room was clean and the breakfast was good too. I would stay again.
Stayed 1 night in Dec 2025

10/10 Excellent

Abbas

Stayed 1 night in Nov 2025

10/10 Excellent

robert, Ames

Travelled with partner
Liked: Cleanliness, staff & service, amenities, property conditions & facilities
The property was excellent. Big shoutout to Taylor who cleaned the snow off my car.
Stayed 2 nights in Nov 2025

8/10 Good

Carly

Liked: Cleanliness, amenities, property conditions & facilities
Overall hotel was clean and nice. Have stayed many times. Cookie hour is a big hit. Only issue is safety. I asked the front desk for a new key after putting my key in the drop box because I forgot something in the room. It was about an hour before checkout time. Instead of looking at my ID and making a new key, or escorting me to the room, they said to just ask housekeeping to let me in. I could have entered any room I wanted to on that floor without question from housekeeping. I find this upsetting and unsafe. That is the oldest scam in the book to enter a room being cleaned or have housekeeping let you in to someone else’s room. A major hotel like this should know better and follow protocol regardless if the front desk doesn’t feel like making a key or double checking an ID. Safety needs to be a top priority for guests.
Stayed 3 nights in Nov 2025

10/10 Excellent

Christopher

Stayed 1 night in Nov 2025

10/10 Excellent

Nancy

Stayed 1 night in Nov 2025

10/10 Excellent

Kalina

Staff was extremely helpful
Stayed 1 night in Nov 2025

10/10 Excellent

Merry

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Exceptional front desk staff! Beautiful property! Excellent room, with spacious bathroom! Everything was perfect!
Stayed 1 night in Nov 2025

10/10 Excellent

Kelly

Liked: Cleanliness
Stayed 1 night in Nov 2025

10/10 Excellent

Robert

Stayed 1 night in Nov 2025

10/10 Excellent

Jessica

Travelled with family
Liked: Cleanliness, staff & service, property conditions & facilities
Clean room. Parking fine. Staff nice. Breakfast is good. Over all stay was okay. Was disappointed in hotels.com due to their room description. If you need a handicap accesible room, book through the hotel. We ended up in a hearing accesible room instead, even though the description was for a handicap accesible room. Hotel made it right the best they could, but they only had a one bed room when we needed two beds.
Stayed 1 night in Nov 2025

10/10 Excellent

Jamie, RockFalls

Liked: Cleanliness, amenities, property conditions & facilities
Great staff!
Stayed 2 nights in Oct 2025

10/10 Excellent

George

Liked: Cleanliness, staff & service, property conditions & facilities
Stayed 2 nights in Oct 2025

6/10 Okay

Michael

Business traveller
Disliked: Staff & service, room comfort
Stayed 3 nights in Oct 2025

10/10 Excellent

Jennifer

Business traveller
Liked: Cleanliness, staff & service, property conditions & facilities, room comfort
Stayed 4 nights in Oct 2025

10/10 Excellent

Zumret

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Excellent
Stayed 2 nights in Aug 2025

8/10 Good

Ruth

Liked: Cleanliness, staff & service, property conditions & facilities
cleaning staff was very helpful and I loved the cookies at night
Stayed 4 nights in Oct 2025

10/10 Excellent

Chena

Business traveller
Liked: Cleanliness, staff & service, property conditions & facilities, room comfort
Very clean safe environment beds were comfortable rooms were nice and clean air-conditioning working well breakfast options for mini cookies in the evening. We’re good. I will stay here again.
Stayed 2 nights in Oct 2025

10/10 Excellent

phillip

Travelled with family
Liked: Cleanliness, staff & service, property conditions & facilities, room comfort
The Hotel is under 10 years old. It still looks grand opening ready in the lobby and the building. The shower, however has mold under the shelfs and corner's. Needed some help all in all , A nice stay.
Stayed 3 nights in Oct 2025

10/10 Excellent

Ashley

Travelled with family
Liked: Cleanliness, staff & service, amenities, property conditions & facilities
The hotel was clean. The breakfast is pretty decent. Several different options to choose from. It’s in a quiet part of town. I would definitely stay there again!
Stayed 3 nights in Oct 2025