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21c Museum Hotel Louisville

4.5 star property

Photo gallery for 21c Museum Hotel Louisville

Front of property
Room (Asleep in the Cyclone)
Breakfast, lunch and dinner served
Room (Asleep in the Cyclone)
Fountain

Reviews

9.2 out of 10
Wonderful

Popular amenities

  • Spa
  • Pet-friendly
  • Free Wi-Fi
  • Air-conditioning
  • Gym

Explore the area

View map
700 W Main Street, Louisville, KY, 40202
  • Place, 21c Museum Hotel
    ‪1 min walk‬
  • Place, Muhammad Ali Center
    ‪3 min walk‬
  • Place, Louisville Slugger Museum
    ‪3 min walk‬
  • Airport, Louisville, KY (SDF-Louisville Intl.)
    ‪10 min drive‬

Room options

View all photos for Deluxe Double Room, 2 Double Beds

Deluxe Double Room, 2 Double Beds

Deluxe Double Room, 2 Double Beds

9.6 out of 10
Exceptional
(30 reviews)
  • 31 sq m
  • Sleeps 4
  • 2 Double Beds

View all photos for Luxury Double Room, 2 Double Beds

Luxury Double Room, 2 Double Beds

Luxury Double Room, 2 Double Beds

9.0 out of 10
Wonderful
(2 reviews)
  • 40 sq m
  • City view
  • Sleeps 4
  • 2 Double Beds

View all photos for Deluxe Room, 1 King Bed

Deluxe Room, 1 King Bed

Deluxe Room, 1 King Bed

9.6 out of 10
Exceptional
(66 reviews)
  • 33 sq m
  • Sleeps 3
  • 1 King Bed

View all photos for Luxury Room, 1 King Bed

Luxury Room, 1 King Bed

Luxury Room, 1 King Bed

9.0 out of 10
Wonderful
(34 reviews)
  • 42 sq m
  • City view
  • Sleeps 3
  • 1 King Bed

View all photos for Suite, Corner

Suite, Corner

Suite, Corner

  • 61 sq m
  • City view
  • Sleeps 3
  • 1 King Bed

View all photos for Room (Asleep in the Cyclone)

Room (Asleep in the Cyclone)

Room (Asleep in the Cyclone)

  • 46 sq m
  • Sleeps 3
  • 1 King Bed

View all photos for Suite (Atrium)

Suite (Atrium)

Suite (Atrium)

  • 54 sq m
  • Sleeps 3
  • 1 King Bed

View all photos for Room, Balcony

Room, Balcony

Room, Balcony

10.0 out of 10
Exceptional
(1 review)
  • 29 sq m
  • City view
  • Sleeps 3
  • 1 King Bed

View all photos for Deluxe Double Room, Accessible

Designer toiletries, hair dryer, bathrobes, towels

Deluxe Double Room, Accessible

9.0 out of 10
Wonderful
(2 reviews)
  • 42 sq m
  • Sleeps 4
  • 2 Double Beds

View all photos for Deluxe Room, 1 King Bed, Accessible

Premium bedding, down duvets, minibar, in-room safe

Deluxe Room, 1 King Bed, Accessible

10.0 out of 10
Exceptional
(1 review)
  • 40 sq m
  • Sleeps 3
  • 1 King Bed

View all photos for Deluxe Room, 1 King Bed, Accessible

Premium bedding, down duvets, minibar, in-room safe

Deluxe Room, 1 King Bed, Accessible

10.0 out of 10
Exceptional
(1 review)
  • 40 sq m
  • Sleeps 3
  • 1 King Bed

View all photos for Apartment, 1 Double Bed (Rooftop)

Apartment, 1 Double Bed (Rooftop)

Apartment, 1 Double Bed (Rooftop)

  • City view
  • Sleeps 4
  • 1 Double Bed

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About the area

Louisville

With a stay at 21c Museum Hotel Louisville, you'll be centrally located in Louisville, just a 3-minute walk from Louisville Slugger Museum and 8 minutes by foot from Kentucky International Convention Center. .This luxury hotel is 0.4 mi (0.7 km) from KFC Yum Center and 6.8 mi (10.9 km) from Kentucky Exposition Center.

What's nearby

  • 21c Museum Hotel - 1 min walk - 0.0 km
  • Muhammad Ali Center - 3 min walk - 0.3 km
  • Louisville Slugger Museum - 3 min walk - 0.3 km
  • Kentucky International Convention Center - 8 min walk - 0.7 km
  • KFC Yum Center - 8 min walk - 0.7 km

Getting around

  • Louisville Intl. Airport (SDF) - 10 min drive

Restaurants

  • ‪Heine Brothers' Coffee - ‬3 min walk
  • ‪Vincenzo's Italian Restaurant - ‬5 min walk
  • ‪Mussel & Burger Bar - ‬1 min walk
  • ‪Sunergos Coffee and Espresso Bar - ‬6 min walk
  • ‪Pokehana - ‬5 min walk

About this property

21c Museum Hotel Louisville

Luxury hotel with a full-service spa and a 24-hour fitness center
21c Museum Hotel Louisville offers 91 accommodations with iPod docking stations and minibars. Beds feature down comforters and premium bedding. 50-inch LCD televisions come with premium cable channels. Bathrooms include bathrobes, designer toiletries, complimentary toiletries, and hair dryers.

This Louisville hotel provides complimentary wired and wireless Internet access. Business-friendly amenities include desks and laptop-compatible safes; free local calls are provided (restrictions may apply). Additionally, rooms include espresso makers and complimentary bottled water. In-room massages and hypo-allergenic bedding can be requested. Housekeeping is provided daily.

Recreational amenities at the hotel include a 24-hour fitness center.

The recreational activities listed below are available either on site or nearby; fees may apply.

21c Spa has 2 treatment rooms. Services include deep-tissue massages, hot stone massages, sports massages, and Swedish massages. The spa is equipped with a sauna and a steam room. The spa is open daily.
Make yourself at home in one of the 91 guestrooms featuring iPod docking stations and minibars. Your bed comes with down comforters and premium bedding. Wired and wireless internet access is complimentary, while 50-inch LCD televisions with cable programming provide entertainment. Private bathrooms have designer toiletries and hair dryers.
Relax at the full-service spa, where you can enjoy massages. Additional features at this hotel include complimentary wireless internet access, concierge services, and gift shops/newsstands.
Grab a bite to eat at Proof on Main, a fine-dining restaurant which features a bar/lounge, or stay in and take advantage of the room service (during limited hours). Full breakfasts are served on weekdays from 7:00 AM to 10:00 AM and on weekends from 8:00 AM to 1:00 PM for a fee.
Featured amenities include complimentary wired internet access, a 24-hour business center, and limo/town car service. Planning an event in Louisville? This hotel has 5000 square feet (465 square meters) of space consisting of conference space and meeting rooms.
Full breakfasts are available for a surcharge on weekdays between 7:00 AM and 10:00 AM and on weekends between 8:00 AM and 1:00 PM.
Proof on Main - This fine-dining restaurant serves breakfast, brunch, lunch, and dinner. Guests can enjoy drinks at the bar.
Room service (during limited hours) is available.

Property amenities

Internet

  • Available in all rooms: Free WiFi and wired internet
  • Available in some public areas: Free WiFi and wired internet

Parking and transport

  • Electric car charging station on site
  • Limo/town car service
  • Valet parking on site (USD 32 per night; includes in/out privileges)
  • Limited on-site valet parking
  • Wheelchair-accessible parking available

Food and drink

  • Full breakfast available for a fee 7:00 AM to 10:00 AM on weekdays and 8:00 AM to 1:00 PM on weekends; USD 5 to 25 per person
  • A bar/lounge
  • A restaurant
  • Coffee and tea in common areas

Restaurants on site

  • Proof on Main

Things to do

  • 24-hour gym
  • Full-service spa
  • Yoga classes

Family friendly

  • In-room cot
  • Laundry facilities
  • Rollaway/extra bed (surcharge)
  • Soundproofed rooms

Conveniences

  • 24-hour front desk
  • ATM
  • Gift shop/newsstand
  • Laundry facilities
  • Luggage storage
  • Safe at front desk

Guest services

  • Concierge services
  • Dry cleaning/laundry service
  • Housekeeping (daily)
  • Multilingual staff
  • Porter/bellhop
  • Tour and ticket assistance

Business services

  • 24-hour business centre
  • 5,000 square feet of conference space
  • Computer station
  • Meeting rooms

Full-service spa

  • 2 treatment rooms
  • Deep-tissue massages
  • Hot stone massages
  • In-room massages
  • Prenatal massages
  • Sauna
  • Spa open daily
  • Sports massages
  • Steam room
  • Swedish massages

Accessibility

  • If you have requests for specific accessibility needs, please contact the property using the information on the reservation confirmation received after booking.
  • Assistive listening devices
  • Braille/raised signage
  • Lift
  • Wheelchair accessibility
  • Wheelchair accessible (may have limitations)
  • Wheelchair-accessible parking
  • Wheelchair-accessible path of travel
  • Wheelchair-accessible registration desk

More

  • 1 building
  • 4 floors
  • At least 80% lighting from LEDs
  • Banquet hall
  • Biodegradable coffee stirrers available
  • Biodegradable drinking straws available
  • Built in 2006
  • Comprehensive food waste policy
  • Double-glazed windows
  • Eco-friendly cleaning products used
  • No plastic coffee stirrers
  • No plastic drinking straws
  • No plastic soft drink bottles
  • No plastic water bottles
  • Reusable cups
  • Reusable tableware
  • Smoke-free property
  • Vegan dining options

Room amenities

Bedroom

  • Blackout drapes
  • Down comforter
  • Free cot
  • Hypo-allergenic bedding
  • Premium bedding
  • Rollaway/extra bed (surcharge)

Bathroom

  • Designer toiletries
  • Dressing gowns
  • Hair dryer
  • Private bathroom
  • Shampoo
  • Soap
  • Toilet paper
  • Toothbrush and toothpaste (on request)
  • Towels provided

Entertainment

  • 50-inch LCD TV with premium cable channels
  • IPod dock

Food and drink

  • Champagne service
  • Espresso maker
  • Free bottled water
  • Limited room service
  • Minibar

More

  • Air conditioning (climate-controlled)
  • Cleaning products are eco-friendly
  • Connecting rooms available
  • Desk
  • Eco-friendly toiletries
  • Free local calls
  • Iron/ironing board
  • Laptop workspace
  • Laptop-compatible safe
  • LED lighting
  • Soundproofed rooms
  • Water-efficient showers

Policies

Check-in

Check-in start time: 4 PM; Check-in end time: midnight
Contactless check-in available
Minimum check-in age: 21

Check-out

Check-out before 11 AM
Contactless check-out available

Special check-in instructions

Front desk staff will greet guests on arrival at the property
Information provided by the property may be translated using automated translation tools

Access methods

Staffed front desk

Pets

Pets allowed for an extra charge of USD 40.00 per accommodation, per stay
Service animals are welcome, and are exempt from fees
Up to 50 lbs per pet
Food and water bowls are available

Children and extra beds

Children are welcome
Rollaway/extra beds are available for USD 30.0 per night
Free cribs are available on request at the property

Payment types

Important information

Fees

You'll be asked to pay the following charges at the property. Fees may include applicable taxes:

  • Service fee: USD 5.00 per accommodation, per stay

We have included all charges provided to us by the property.

Optional extras

  • Fee for full breakfast: approximately USD 5 to 25 per person
  • Valet parking fee: USD 32 per night (in/out privileges)
  • Pet fee: USD 40.00 per accommodation, per stay
  • Service animals are exempt from fees
  • Rollaway bed fee: USD 30.0 per night

The above list may not be comprehensive. Fees and deposits may not include tax and are subject to change.

You need to know

Extra-person charges may apply and vary depending on property policy
Government-issued photo identification and a credit card may be required at check-in for incidental charges
Special requests are subject to availability upon check-in and may incur additional charges; special requests cannot be guaranteed
The name on the credit card used at check-in to pay for incidentals must be the primary name on the guestroom reservation
This property accepts credit cards; cash is not accepted
This property uses eco-friendly cleaning products
Safety features at this property include a carbon monoxide detector, a fire extinguisher, a smoke detector, a security system, a first aid kit, and window guards
This property affirms that it follows the cleaning and disinfection practices of ALLSAFE (Accor Hotels)

We should mention

Reservations are required for massage services; reservations can be made by contacting the property prior to arrival, using the contact information on the booking confirmation
The property has connecting/adjoining rooms, which are subject to availability and can be requested by contacting the property using the number on the booking confirmation
This property welcomes guests of all sexual orientations and gender identities (LGBTQ+ friendly)

Property is also known as

21c Hotel Louisville
21c Hotel Museum
21c Louisville Hotel
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Louisville 21c Hotel
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Museum Hotel 21c
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21c Museum Hotel Louisville Reviews

Reviews

9.2

Wonderful

Rating 10 - Excellent. 762 out of 1000 reviews
Rating 8 - Good. 135 out of 1000 reviews
Rating 6 - Okay. 62 out of 1000 reviews
Rating 4 - Poor. 23 out of 1000 reviews
Rating 2 - Terrible. 18 out of 1000 reviews

9.6/10

Cleanliness

9.4/10

Staff & service

9.0/10

Amenities

9.6/10

Property conditions & facilities

Reviews

10/10 Excellent

Natalie

Liked: Cleanliness, staff & service, property conditions & facilities
Stayed 3 nights in Oct 2025

10/10 Excellent

Stephanie

Travelled with group
Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Loved the strange art. I thought the building maintained the character I was expecting by the name and the reviews. Gym was actually better than the reviews.
Stayed 2 nights in Oct 2025

10/10 Excellent

earl

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Perfect location for walking Louisville
Stayed 4 nights in Oct 2025

8/10 Good

Pamela

Liked: Cleanliness, staff & service, property conditions & facilities, room comfort
Nice art
Stayed 1 night in Oct 2025

6/10 Okay

Kevin

Stayed 3 nights in Oct 2025

10/10 Excellent

Shelley

Travelled with partner
Liked: Cleanliness, staff & service, amenities, property conditions & facilities
We only stayed 1 night, but everything was excellent
Stayed 1 night in Oct 2025

10/10 Excellent

Courtney

Liked: Cleanliness
Stayed 1 night in Sep 2025

8/10 Good

mirtha

Travelled with partner
Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Good location
Stayed 2 nights in Oct 2025

10/10 Excellent

Ralph

Stayed 1 night in Sep 2025

8/10 Good

mark

Travelled with family, Travelled with partner
Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Price was too high compared to similar hotels.
Stayed 2 nights in Sep 2025

2/10 Terrible

Uzeir

Stayed 1 night in Sep 2025

10/10 Excellent

Jeannette

Liked: Cleanliness, staff & service, property conditions & facilities
Great stay overall.
Stayed 2 nights in Sep 2025

10/10 Excellent

Maxine

Travelled with partner
Liked: Cleanliness, staff & service, amenities, property conditions & facilities
I stayed in a King Deluxe room and it exceeded expectations. Spacious with high ceilings and floor-to-ceiling windows, the room was both beautiful and comfortable. The historic building itself feels like a work of art, blending industrial character with modern design. The staff were incredibly friendly and accommodating, showcasing true Louisville hospitality. What makes this hotel so unique is that it doubles as an art museum. Displays of contemporary art and sculptures are found throughout, and even the lobby bathroom is an experience with mirrored installations that play with perspective. The amenities are exceptional. I’ve never stayed in a hotel that offers both a sauna and a steam room—perfect after a workout or simply to relax and recharge. The on-site restaurant, Proof on Main, also deserves praise. The hotel provides drink vouchers for complimentary bourbon tastings, a thoughtful touch in bourbon country. The food was outstanding, with every meal delicious. The chicken dish especially impressed me for being moist, flavorful, and far beyond standard hotel dining. If there’s one small note, the hotel carries a distinctive scent, likely from the historic structure, though it wasn’t unpleasant. Overall, 21c Museum Hotel is a must-stay. Between the spacious rooms, inspiring art, excellent dining, relaxing amenities, and prime location near restaurants, coffee shops, shops, and the waterfront, it offers an unforgettable experience.
Stayed 4 nights in Sep 2025

10/10 Excellent

Jennifer

Travelled with family
Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Amazing location and great hotel. Staff was great. Restaurant was delicious. Great location on Main Street!!
Stayed 4 nights in Sep 2025

10/10 Excellent

Jennifer

Travelled with family
Liked: Cleanliness, staff & service, property conditions & facilities
Room was very clean and staff were very friendly.
Stayed 1 night in Sep 2025

10/10 Excellent

jennifer

Loved it!!
Stayed 2 nights in Sep 2025

10/10 Excellent

Jessica

Travelled with partner
Liked: Cleanliness, staff & service, property conditions & facilities
Shout out to the valet staff, super friendly and helpful and truly made the weekend great.
Stayed 3 nights in Sep 2025

10/10 Excellent

Kimberley, Seattle

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Fun place to stay! Eclectic, unique and eccentric decor. Really enjoyed the location and convenient, walkable access.
Stayed 3 nights in Sep 2025

10/10 Excellent

Eric

Liked: Cleanliness, staff & service, property conditions & facilities
The art museum is pretty cool. Staff were super nice.
Stayed 5 nights in Sep 2025

10/10 Excellent

Michael Sheridan, Chicago

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Very cool art in a perfect location, walkable to so many great venues. Very friendly, helpful staff. The adjacent restaurant, Proof, was cool and delicious. The rooms were well appointed with in room safe, mini fridge, nice shower and comfortable beds. We would definitely stay here again.
Stayed 2 nights in Sep 2025

10/10 Excellent

Heather

Travelled with partner
Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Nice property. Room was comfortable, easy check in and check out. Staff were pleasant and atmosphere was cool.
Stayed 2 nights in Sep 2025

10/10 Excellent

Cristina

Travelled with group
Liked: Cleanliness, staff & service, property conditions & facilities, room comfort

Worth every mile!

I can’t say enough amazing things about this hotel. It in itself is worth the trip. The exhibits are amazing, the staff were everything you want them to be. They recalled who we were, why we were there…. I will most definitely be returning.
Stayed 2 nights in Sep 2025

10/10 Excellent

Julie

Liked: Cleanliness, staff & service, property conditions & facilities, room comfort
Stayed 2 nights in Sep 2025

10/10 Excellent

Jeffrey

Stayed 2 nights in Aug 2025

10/10 Excellent

Jean-Paul

Liked: Cleanliness, staff & service, property conditions & facilities, room comfort
Stayed 3 nights in Sep 2025