Book Santee hotels

Start date: Check-in selected.
To Date
End date: Check-out

More Flash, Less Cash - Take advantage of our Price Pledge** (even on luxey stays)

We keep it easy with the option to pay now or later on select accommodation

Book up 'til the last second - millions of rooms to crash tonight^

Check hotel availability in Santee

Cheap Santee hotels

Baymont by Wyndham Santee

Baymont by Wyndham Santee

2.5 out of 5
249 Britain Street Santee SC
Fully refundableReserve now, pay when you stay
The price is NZ$138 per night from 1 Feb to 2 Feb
NZ$138
1 Feb - 2 Feb
includes taxes & fees
Stay at this business-friendly hotel in Santee. Enjoy free breakfast, free Wi-Fi and free parking. Our guests praise the breakfast and the helpful staff in their ...
Opens in a new windowBaymont by Wyndham Santee
Tru By Hilton Santee

Tru By Hilton Santee

2.5 out of 5
263 Britain St. and 273 Britain St. Santee SC
Fully refundableReserve now, pay when you stay
The price is NZ$192 per night from 9 Feb to 10 Feb
NZ$192
9 Feb - 10 Feb
includes taxes & fees
Stay at this hotel in Santee. Enjoy free breakfast, free Wi-Fi and free parking. Our guests praise the breakfast and the helpful staff in their reviews. Popular ...
Opens in a new windowTru By Hilton Santee
Hampton Inn Santee-I-95

Hampton Inn Santee-I-95

2.5 out of 5
9060 Old Number Six Hwy Santee SC
Fully refundableReserve now, pay when you stay
The price is NZ$228 per night from 22 Feb to 23 Feb
NZ$228
22 Feb - 23 Feb
includes taxes & fees
Stay at this hotel in Santee. Enjoy free breakfast, free Wi-Fi and free parking. Our guests praise the breakfast and the helpful staff in their reviews. Popular ...
Opens in a new windowHampton Inn Santee-I-95
Save an average of 15% on thousands of hotels when you're signed in
Fairfield Inn & Suites by Marriott Santee

Fairfield Inn & Suites by Marriott Santee

2.5 out of 5
9074 Old Number Six Hwy Santee SC
The price is NZ$223 per night from 8 Feb to 9 Feb
NZ$223
8 Feb - 9 Feb
includes taxes & fees
Stay at this hotel in Santee. Enjoy free breakfast, free Wi-Fi and free parking. Our guests praise the breakfast and the helpful staff in their reviews. Popular ...
Opens in a new windowFairfield Inn & Suites by Marriott Santee
Comfort Inn & Suites Santee

Comfort Inn & Suites Santee

2.5 out of 5
221 Britain St Santee SC
Fully refundableReserve now, pay when you stay
The price is NZ$174 per night from 9 Feb to 10 Feb
NZ$174
9 Feb - 10 Feb
includes taxes & fees
Stay at this hotel in Santee. Enjoy free breakfast, free Wi-Fi and free parking. Our guests praise the helpful staff in their reviews. Popular attractions Santee ...
Opens in a new windowComfort Inn & Suites Santee
Best Western Plus Santee Inn

Best Western Plus Santee Inn

2.5 out of 5
I 95 Exit 98 Santee SC
Fully refundableReserve now, pay when you stay
The price is NZ$219 per night from 8 Feb to 9 Feb
NZ$219
8 Feb - 9 Feb
includes taxes & fees
Stay at this business-friendly hotel in Santee. Enjoy free breakfast, free parking and a fitness centre. Our guests praise the breakfast and the helpful staff ...
Opens in a new windowBest Western Plus Santee Inn
Holiday Inn Santee by IHG

Holiday Inn Santee by IHG

3 out of 5
139 Bradford Blvd Santee SC
Fully refundable
The price is NZ$216 per night from 9 Feb to 10 Feb
NZ$216
9 Feb - 10 Feb
includes taxes & fees
Stay at this golf hotel in Santee. Enjoy free Wi-Fi, free parking and breakfast (surcharge). Our guests praise the helpful staff and the clean rooms in their ...
Opens in a new windowHoliday Inn Santee by IHG
Quality Inn & Suites

Quality Inn & Suites

2.5 out of 5
8929 Old Number Six Highway Santee SC
Fully refundableReserve now, pay when you stay
The price is NZ$109 per night from 8 Feb to 9 Feb
NZ$109
8 Feb - 9 Feb
includes taxes & fees
Stay at this business-friendly hotel in Santee. Enjoy free breakfast, free Wi-Fi and free parking. Our guests praise the helpful staff and the clean rooms in ...
Opens in a new windowQuality Inn & Suites
Ramada by Wyndham Santee I-95

Ramada by Wyndham Santee I-95

2 out of 5
123 Mall Street Santee SC
Fully refundableReserve now, pay when you stay
The price is NZ$148 per night from 8 Feb to 9 Feb
NZ$148
8 Feb - 9 Feb
includes taxes & fees
Stay at this golf hotel in Santee. Enjoy free Wi-Fi, free parking and a 24-hour fitness centre. Popular attractions Santee Cooper Country Club and Santee National ...
Opens in a new windowRamada by Wyndham Santee I-95
Don't see what you're looking for?
See all available properties in Santee
View all properties
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Hotels In Santee

About to take off and visit Orangeburg? Keen to book a bed in Santee? Currently, we have 11 places to base yourself within a 10-kilometre distance of the main part of Santee.

Stay close to the heart of Santee. Accommodations here include the Holiday Inn Santee and Hampton Inn Santee I-95.

Outlaying less on your hotel often means more dough for fun. Why not check out the Super 8 Santee, Red Roof Inn Santee and Rodeway Inn?

35 kilometres away from the middle of Santee is the Hampton Inn Manning. Alternatively, the Comfort Inn & Suites Santee is located 2 kilometres away. If you'd prefer, you could make a booking at the Best Western Plus Santee Inn or the Quality Inn And Suites.

Looking to travel further afield? You're in luck! South Carolina Midlands has many other attractions to keep you busy throughout your stay. If you're a nature lover, you won't want to miss South Carolina Midlands's rolling hills. If nature's not your thing, head to the area's historic mansions and gardens. Or join the locals hiking, zip-lining and horse riding while you are here.

You will find various accommodation options in Stilton, situated 35 kilometres to the west of Santee. The Comfort Inn & Suites and Holiday Inn Express Hotel & Suites Orangeburg are some of the hotels here.

Just because you are travelling, doesn't mean you can't enjoy your obsession for sports. Colonial Life Arena can be found 80 kilometres to the northwest of Santee. The Sheraton Columbia Downtown Hotel and the Hilton Columbia Center are good options if you hope to get amongst it.

Charleston International Airport can be found 75 kilometres away from the centre of Santee. Should you wish to stay nearby, you can easily secure a room at the Embassy Suites North Charleston - Airport/Hotel & Convention or the Residence Inn Charleston Airport.

Santee hotels essential information

Accommodation
303 hotels
Lowest Price
NZ$109
Highest Price
NZ$228
Popular hotels
Baymont by Wyndham Santee, Tru By Hilton Santee, Hampton Inn Santee-I-95, Fairfield Inn & Suites by Marriott Santee, Comfort Inn & Suites Santee, Best Western Plus Santee Inn, Holiday Inn Santee by IHG, Quality Inn & Suites, Ramada by Wyndham Santee I-95

Most recent Santee hotel reviews

**Terms and Conditions apply.
^Subject to availability and chosen travel dates.