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Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG

2.5 star property

Photo gallery for Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG

Exterior
Exterior
Premium bedding, down duvets, pillow-top beds, in-room safe
Indoor pool, open 8 AM to 11 PM, pool loungers
Free breakfast

Reviews

9.4 out of 10
Exceptional

Popular amenities

  • Laundry
  • Housekeeping

Explore the area

View map
3253 William Street, Cape Girardeau, MO, 63701
  • Place, Saint Francis Medical Center
    ‪6 min walk‬
  • Place, Southeast Missouri State University
    ‪6 min drive‬
  • Place, Isle Casino Cape Girardeau
    ‪8 min drive‬
  • Airport, Cape Girardeau, MO (CGI-Cape Girardeau Municipal)
    ‪5 min drive‬

Room options

View all photos for Suite, 2 Queen Beds, Accessible (Roll-In Shower)

Suite, 2 Queen Beds, Accessible (Roll-In Shower)

Suite, 2 Queen Beds, Accessible (Roll-In Shower)

8.0 out of 10
Very good
(5 reviews)
  • 37 sq m
  • Sleeps 6
  • 2 Queen Beds

View all photos for Suite, 1 King Bed, Accessible (Roll-In Shower)

Premium bedding, down duvets, pillow-top beds, in-room safe

Suite, 1 King Bed, Accessible (Roll-In Shower)

9.4 out of 10
Exceptional
(6 reviews)
  • Sleeps 2
  • 1 King Bed

View all photos for Suite, 1 King Bed

Premium bedding, down duvets, pillow-top beds, in-room safe

Suite, 1 King Bed

9.6 out of 10
Exceptional
(32 reviews)
  • Sleeps 2
  • 1 King Bed

View all photos for Suite, 2 Queen Beds

Premium bedding, down duvets, pillow-top beds, in-room safe

Suite, 2 Queen Beds

9.6 out of 10
Exceptional
(53 reviews)
  • Sleeps 6
  • 2 Queen Beds

View all photos for Suite, 2 Queen Beds, Accessible (Mobility)

Premium bedding, down duvets, pillow-top beds, in-room safe

Suite, 2 Queen Beds, Accessible (Mobility)

9.4 out of 10
Exceptional
(14 reviews)
  • 37 sq m
  • Sleeps 6
  • 2 Queen Beds

View all photos for Standard Room, 1 Queen Bed

Premium bedding, down duvets, pillow-top beds, in-room safe

Standard Room, 1 Queen Bed

9.2 out of 10
Wonderful
(5 reviews)
  • 37 sq m
  • Sleeps 2
  • 1 Queen Bed

View all photos for Standard Room

Premium bedding, down duvets, pillow-top beds, in-room safe

Standard Room

8.4 out of 10
Very good
(5 reviews)
  • 37 sq m
  • Sleeps 2
  • 1 King Bed

View all photos for Suite, 1 Bedroom (Feature)

Premium bedding, down duvets, pillow-top beds, in-room safe

Suite, 1 Bedroom (Feature)

10.0 out of 10
Exceptional
(1 review)
  • Sleeps 2
  • 1 Queen Bed

View all photos for Suite, 1 King Bed, Accessible (Mobility)

Premium bedding, down duvets, pillow-top beds, in-room safe

Suite, 1 King Bed, Accessible (Mobility)

10.0 out of 10
Exceptional
(2 reviews)
  • Sleeps 2
  • 1 King Bed

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About the area

Cape Girardeau

With a stay at Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG in Cape Girardeau, you'll be near the airport, within a 10-minute drive of Mississippi River and Saint Francis Medical Center. .This spa hotel is 2.4 mi (3.8 km) from Cape Splash Family Aquatic Center and 2.4 mi (3.9 km) from Saint Francis Healthcare System.

What's nearby

  • Saint Francis Medical Center - 6 min walk - 0.6 km
  • Southeast Missouri Hospital - 5 min drive - 5.3 km
  • Southeast Missouri State University - 6 min drive - 6.3 km
  • Isle Casino Cape Girardeau - 8 min drive - 9.1 km
  • Show Me Center - 9 min drive - 9.1 km

Getting around

  • Cape Girardeau, MO (CGI-Cape Girardeau Municipal) - 10 min drive

Restaurants

  • ‪Chick-fil-A - ‬7 min walk
  • ‪Rhodes - ‬20 min walk
  • ‪McDonald's - ‬10 min walk
  • ‪White Castle - ‬10 min walk
  • ‪Wings Etc. - ‬9 min walk

About this property

Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG

Hotel in Cape Girardeau with a full-service spa and free breakfast
Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG offers 102 accommodations with safes and coffee/tea makers. Accommodations offer separate sitting areas. Pillowtop beds feature down comforters and premium bedding. A pillow menu is available. 52-inch flat-screen televisions come with premium cable channels. Bathrooms include complimentary toiletries and hair dryers.

Guests can surf the web using the complimentary wired and wireless Internet access. Business-friendly amenities include desks and phones; free local calls are provided (restrictions may apply). Housekeeping is provided daily.

Recreational amenities at the hotel include an indoor pool and a fitness center.
Guests can indulge in a pampering treatment at the hotel's full-service spa.
Make yourself at home in one of the 102 guestrooms featuring microwaves and flat-screen televisions. Your pillowtop bed comes with down comforters and premium bedding. Complimentary wired and wireless internet access keeps you connected, and cable programming provides entertainment. Private bathrooms have complimentary toiletries and hair dryers.
Take time to pamper yourself with a visit to the full-service spa. If you're looking for recreational opportunities, you'll find an indoor pool and a fitness center. Additional features at this hotel include complimentary wireless internet access, a banquet hall, and a vending machine.
A complimentary breakfast is included.
Featured amenities include complimentary wired internet access, a business center, and complimentary newspapers in the lobby. Planning an event in Cape Girardeau? This hotel has 118 square feet (11 square meters) of space consisting of conference space and a meeting room. Free self parking is available onsite.
A complimentary breakfast is offered.

Property amenities

Internet

  • Available in all rooms: Free WiFi and wired internet
  • Available in some public areas: Free WiFi and wired internet

Parking and transport

  • Free self parking on site
  • Wheelchair-accessible parking available

Food and drink

  • Free breakfast available

Things to do

  • Full-service spa
  • Gym
  • Indoor pool

Family friendly

  • In-room microwave
  • Indoor pool
  • Laundry facilities
  • Mini-fridge

Conveniences

  • 24-hour front desk
  • Free newspapers in lobby
  • Laundry facilities
  • Luggage storage
  • Safe at front desk
  • Vending machine

Guest services

  • Dry cleaning/laundry service
  • Housekeeping (daily)
  • Porter/bellhop

Business services

  • 118 square feet of conference space
  • Business centre
  • Meeting room

Outdoors

  • Pool loungers

Accessibility

  • If you have requests for specific accessibility needs, please contact the property using the information on the reservation confirmation received after booking.
  • Assistive listening devices
  • Braille/raised signage
  • Visual fire alarm
  • Well-lit path to entrance
  • Wheelchair accessible (may have limitations)
  • Wheelchair-accessible parking
  • Wheelchair-accessible path of travel
  • Wheelchair-accessible path to lift

More

  • 1 building
  • 4 floors
  • Banquet hall
  • Smoke-free property

Room amenities

Bedroom

  • Down comforter
  • Pillow menu
  • Pillowtop mattress
  • Premium bedding

Bathroom

  • Free toiletries
  • Hair dryer
  • Private bathroom
  • Shampoo
  • Soap
  • Toilet paper
  • Towels provided

Entertainment

  • 52-inch flat-screen TV with premium cable channels

Food and drink

  • Coffee/tea maker
  • Microwave
  • Mini-fridge

More

  • Air conditioning (climate-controlled)
  • Connecting rooms available
  • Desk
  • Free local calls
  • Iron/ironing board
  • Laptop workspace
  • Phone
  • Safe
  • Separate sitting area

Policies

Check-in

Check-in start time: 3:00 PM; Check-in end time: anytime
Contactless check-in available
Minimum check-in age: 21

Check-out

Check-out before 11 AM
Contactless check-out available

Special check-in instructions

Front desk staff will greet guests on arrival at the property
Information provided by the property may be translated using automated translation tools

Access methods

Staffed front desk

Pets

Pets not allowed

Children and extra beds

Children are welcome
Cribs (infant beds) are not available

Payment types

Important information

You need to know

Extra-person charges may apply and vary depending on property policy
Government-issued photo identification and a credit card, debit card, or cash deposit may be required at check-in for incidental charges
Special requests are subject to availability upon check-in and may incur additional charges; special requests cannot be guaranteed
This property accepts credit cards; cash is not accepted
Cashless transactions are available
Safety features at this property include a smoke detector
This property affirms that it follows the cleaning and disinfection practices of Clean Promise (IHG)

We should mention

Pool access available from 8 AM to 11 PM
The property has connecting/adjoining rooms, which are subject to availability and can be requested by contacting the property using the number on the booking confirmation
This property welcomes guests of all sexual orientations and gender identities (LGBTQ+ friendly)

Property is also known as

Holiday Inn Express Cape Girardeau I-55
Holiday Inn Express Hotel Cape Girardeau I-55
Holiday Inn Hotel I-55
Holiday Inn Express Hotel Suites Cape Girardeau I 55
Inn Express Cape Girarau I55
Holiday Inn Express Hotel Suites Cape Girardeau I 55
Holiday Inn Express Hotel Suites Cape Girardeau I 55 by IHG

Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG Reviews

Reviews

9.4

Exceptional

Rating 10 - Excellent. 780 out of 1001 reviews
Rating 8 - Good. 149 out of 1001 reviews
Rating 6 - Okay. 39 out of 1001 reviews
Rating 4 - Poor. 16 out of 1001 reviews
Rating 2 - Terrible. 17 out of 1001 reviews

9.6/10

Cleanliness

9.6/10

Staff & service

9.2/10

Amenities

9.6/10

Property conditions & facilities

9.4/10

Eco-friendliness

Reviews

8/10 Good

Terri

Stayed 3 nights in May 2025

8/10 Good

David, Caruthersville

Travelled with partner
Liked: Cleanliness, staff & service, amenities
The hotel itself was very warm, along with the room which the thermostat did not work correctly. But no complaints other than that
Stayed 1 night in Sep 2025

10/10 Excellent

Shana

Travelled with family
Liked: Cleanliness, staff & service, property conditions & facilities, room comfort
Stayed 1 night in Aug 2025

10/10 Excellent

Darlene Cassidy

Liked: Cleanliness, staff & service, property conditions & facilities, room comfort

Nice hotel

Great
Stayed 1 night in Sep 2025

10/10 Excellent

Richie

Stayed 1 night in Sep 2025

10/10 Excellent

Douglas

Liked: Cleanliness, staff & service, property conditions & facilities
Stayed 1 night in Sep 2025

10/10 Excellent

Suzanne

Travelled with family
Liked: Staff & service, property conditions & facilities
Everything was good except for our bathroom not being really clean.
Stayed 1 night in Sep 2025

10/10 Excellent

Laura

Liked: Cleanliness, staff & service, property conditions & facilities, room comfort

Lovely stay

Our stay was wonderful. The rooms are so nice. Bed was comfortable. The jaccuzi tub is excellent. The free breakfast was lovely. Even had healthy options with turkey sausage and egg white omelets. Delicious.
Stayed 1 night in Aug 2025

10/10 Excellent

Christian

Liked: Cleanliness, staff & service, property conditions & facilities
Stayed 1 night in Aug 2025

10/10 Excellent

Carey

Liked: Cleanliness, staff & service, property conditions & facilities, room comfort
Very Friendly check in Parking lot was very Safe A lot of know restaurants within walking distance from Hotel,Very Clean.
Stayed 2 nights in Aug 2025

10/10 Excellent

Gay

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Felt like I was in a mansion.
Stayed 1 night in Aug 2025

6/10 Okay

Jessica

Stayed 1 night in Aug 2025

8/10 Good

stephanie

Liked: Cleanliness, staff & service, property conditions & facilities, room comfort
Stayed 1 night in Aug 2025

10/10 Excellent

Amy Lynn

Travelled with family
Liked: Cleanliness, staff & service, amenities, property conditions & facilities
It was great had a wonderful time with my in-laws.
Stayed 2 nights in Aug 2025

10/10 Excellent

COYT

Liked: Cleanliness, staff & service, property conditions & facilities, room comfort
Stayed 1 night in Aug 2025

10/10 Excellent

Nashon

Stayed 3 nights in Jul 2025

10/10 Excellent

Jessica

Travelled with family
Liked: Amenities
The hotel was very nice and the staff were super helpful. I would stay here again!
Stayed 1 night in Aug 2025

10/10 Excellent

Dalton

Liked: Cleanliness
Stayed 1 night in Aug 2025

10/10 Excellent

Alicia

Travelled with family
Liked: Cleanliness, staff & service, property conditions & facilities, room comfort
Stayed 1 night in Jul 2025

10/10 Excellent

Robert

Travelled with family
Liked: Amenities
Great room and breakfast
Stayed 1 night in Aug 2025

10/10 Excellent

Robert

Liked: Property conditions & facilities
Stayed 1 night in Aug 2025

10/10 Excellent

Evelyn

Travelled with family
Liked: Cleanliness, staff & service, property conditions & facilities, room comfort
Stayed 1 night in Jul 2025

10/10 Excellent

Jill

Travelled with family, Travelled with partner
Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Rooms are very nice and spacious. Liked the welcome cookies. Breakfast buffet had lots of options!
Stayed 1 night in Aug 2025

8/10 Good

Stephanie

Stayed 1 night in Aug 2025

6/10 Okay

Erica

Travelled with family and small children
Liked: Staff & service, amenities, property conditions & facilities
We thought there was going to be a hot tub! Also found hairs around in the bathroom floor and tub
Stayed 1 night in Aug 2025